PDGFRα/β and VEGFR2 polymorphisms in colorectal cancer: incidence and implications in clinical outcome

<p>Abstract</p> <p>Background</p> <p>Angiogenesis plays an essential role in tumor growth and metastasis, and is a major target in cancer therapy. VEGFR and PDGFR are key players involved in this process. The purpose of this study was to assess the incidence of genetic...

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Detalhes bibliográficos
Main Authors: Estevez-Garcia Purificacion, Castaño Angel, Martin Ana C, Lopez-Rios Fernando, Iglesias Joaquin, Muñoz-Galván Sandra, Lopez-Calderero Iker, Molina-Pinelo Sonia, Pastor Maria D, Carnero Amancio, Paz-Ares Luis, Garcia-Carbonero Rocio
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2012-11-01
Colecção:BMC Cancer
Assuntos:
VEGFR
PDGFR
SNP
Colorectal cancer
Angiogenesis
Prognosis
Acesso em linha:http://www.biomedcentral.com/1471-2407/12/514
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