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Molecular Mechanism of Matrine from Sophora alopecuroides in the Reversing Effect of Multi-Anticancer Drug Resistance in K562/ADR Cells

Multidrug resistance is the main obstacle to current chemotherapies. In this study, we evaluated the reversing effect of matrine, the principal alkaloid derived from Sophora alopecuroides, on chemoresistant leukemia K562/ADR cells. Matrine in a range of the nontoxic concentration was employed in the...

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Autores principales: Zhi Chen, Nobuhiro Nishimura, Takayuki Okamoto, Koichiro Wada, Kohji Naora
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Limited 2019-01-01
Colección:BioMed Research International
Acceso en línea:http://dx.doi.org/10.1155/2019/1269532
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