Downregulation of miR-200a induces EMT phenotypes and CSC-like signatures through targeting the β-catenin pathway in hepatic oval cells.

Hepatocellular carcinoma (HCC) can be derived from malignant transformed adult hepatic progenitor cells. However, the regulatory factors and molecular mechanisms underlying the process are not well defined. Our previous microRNA (miRNA) microarray analysis revealed a significant decrease of miR-200a...

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Bibliographic Details
Main Authors: Jie Liu, Bai Ruan, Nan You, Qike Huang, Weihui Liu, Zheng Dang, Weihua Xu, Ti Zhou, Ru Ji, Yang Cao, Xia Li, Desheng Wang, Kaishan Tao, Kefeng Dou
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3829824?pdf=render
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