DOPAMINE RECEPTOR D2 (DRD2) IN PERIPHERAL BLOOD LYMPHOCYTES AS BIOMARKER OF RESPONSE TO ANTIPSYCHOTIC MEDICATION

Introduction. Despite the evolution of antipsychotic drugs, the problem of the therapy effectiveness and safety of schizophrenia spectrum disorders and comorbid conditions is very acute. The dopamine receptor D2 gene (DRD2) is one of the key targets of modern pharmacogenetic studies of mental disord...

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Main Authors: M. N. Grunina, A. M. Zabotina, A. S. Zhuravlev, M. M. Pchelina, E. V. Volkova, R. F. Nasyrova, A. E. Taraskina, E. M. Krupitsky
Formato: Artigo
Idioma:Russo
Publicado em: Academician I.P. Pavlov First St. Petersburg State Medical University 2020-05-01
Colecção:Učenye Zapiski Sankt-Peterburgskogo Gosudarstvennogo Medicinskogo Universiteta im. Akad. I.P. Pavlova
Assuntos:
drd2 gene
mrna levels
–141с ins/del
schizophrenia spectrum disorders
comorbidity
alcohol dependence syndrome
antipsychotic drugs
peripheral blood lymphocytes
antipsychotic-induced weight gain
Acesso em linha:https://www.sci-notes.ru/jour/article/view/657
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