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Engineering the vaccinia virus L1 protein for increased neutralizing antibody response after DNA immunization

<p>Abstract</p> <p>Background</p> <p>The licensed smallpox vaccine, comprised of infectious vaccinia virus, has associated adverse effects, particularly for immunocompromised individuals. Therefore, safer DNA and protein vaccines are being investigated. The L1 protein,...

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Hlavní autoři: Moss Bernard, Irvine Kari R, Wyatt Linda S, Shinoda Kaori
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2009-03-01
Edice:Virology Journal
On-line přístup:http://www.virologyj.com/content/6/1/28
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