Experimental setup for the identification of mitochondrial protease substrates by shotgun and top-down proteomics

Mitochondria possess a proteolytic system that contributes to the regulation of mitochondrial dynamics, mitochondrial biogenesis and mitophagy. We aimed at the identification by bottom-up proteomics of altered protein processing due to the activation of mitochondrial proteases in a cellular model of...

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Detaylı Bibliyografya
Asıl Yazarlar: Alice Di Pierro, Heather Bondi, Chiara Monti, Luisa Pieroni, Enrico Cilio, Andrea Urbani, Tiziana Alberio, Mauro Fasano, Maurizio Ronci
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2016-06-01
Seri Bilgileri:EuPA Open Proteomics
Konular:
Mitochondria
Protease
Shotgun
Top-down
Electroelution
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2212968516300150
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