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Identification of a CCR5-expressing T cell subset that is resistant to R5-tropic HIV infection.

Infection with HIV-1 perturbs homeostasis of human T cell subsets, leading to accelerated immunologic deterioration. While studying changes in CD4(+) memory and naïve T cells during HIV-1 infection, we found that a subset of CD4(+) effector memory T cells that are CCR7(-)CD45RO(-)CD45RA(+) (referred...

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Detalhes bibliográficos
Main Authors: Kyra Oswald-Richter, Stacy M Grill, Mindy Leelawong, Michelle Tseng, Spyros A Kalams, Todd Hulgan, David W Haas, Derya Unutmaz
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2007-04-01
Colecção:PLoS Pathogens
Acesso em linha:http://europepmc.org/articles/PMC1857714?pdf=render
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