E2-2 Dependent Plasmacytoid Dendritic Cells Control Autoimmune Diabetes.

Autoimmune diabetes is a consequence of immune-cell infiltration and destruction of pancreatic β-cells in the islets of Langerhans. We analyzed the cellular composition of the insulitic lesions in the autoimmune-prone non-obese diabetic (NOD) mouse and observed a peak in recruitment of plasmacytoid...

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Bibliographic Details
Main Authors: Lisbeth Hansen, Anja Schmidt-Christensen, Shashank Gupta, Nina Fransén-Pettersson, Tine D Hannibal, Boris Reizis, Pere Santamaria, Dan Holmberg
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4666626?pdf=render
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