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Drug Repositioning with GraphSAGE and Clustering Constraints Based on Drug and Disease Networks

The understanding of therapeutic properties is important in drug repositioning and drug discovery. However, chemical or clinical trials are expensive and inefficient to characterize the therapeutic properties of drugs. Recently, artificial intelligence (AI)-assisted algorithms have received extensiv...

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Detalhes bibliográficos
Main Authors: Yuchen Zhang, Xiujuan Lei, Yi Pan, Fang-Xiang Wu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Pharmacology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2022.872785/full
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