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Pine bark extract (Pycnogenol®) suppresses cigarette smoke-induced fibrotic response via transforming growth factor-β1/Smad family member 2/3 signaling

Abstract Chronic obstructive pulmonary diseases (COPD) is an important disease featured as intense inflammation, protease imbalance, and air flow limitation and mainly induced by cigarette smoke (CS). In present study, we explored the effects of Pycnogenol® (PYC, pine bark extract) on pulmonary fibr...

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Detalhes bibliográficos
Main Authors: Je-Won Ko, Na-Rae Shin, Sung-Hyeuk Park, Joong-Sun Kim, Young-Kwon Cho, Jong-Choon Kim, In-Sik Shin, Dong-Ho Shin
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-12-01
Colecção:Laboratory Animal Research
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Acesso em linha:http://link.springer.com/article/10.5625/lar.2017.33.2.76
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