Aquaporin-3 Inhibition Reduces the Growth of NSCLC Cells Induced by Hypoxia

Background/Aims: Non-small cell lung cancer (NSCLC) is the leading cause of death worldwide. Although aquaporin-3 (AQP3) is widely distributed in mammalian tissues and over-expressed in NSCLC cells, there are limited studies on the effects of AQP3 knockdown on NSCLC cells under hypoxic conditions. M...

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Main Authors: Shu-Ying Hou, Yan-Ping Li, Jin-Hua Wang, Song-Ling Yang, Ying Wang, Yang Wang, Ye Kuang
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Physiol Biochem Press GmbH & Co KG 2016-01-01
Colecção:Cellular Physiology and Biochemistry
Assuntos:
Non-small cell lung cancer
ERK
Aquaporin-3
HIF-1α
VEGF
Acesso em linha:http://www.karger.com/Article/FullText/438615
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