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Gene Transcriptional and Metabolic Profile Changes in Mimetic Aging Mice Induced by D-Galactose.

D-galactose injection has been shown to induce many changes in mice that represent accelerated aging. This mouse model has been widely used for pharmacological studies of anti-aging agents. The underlying mechanism of D-galactose induced aging remains unclear, however, it appears to relate to glucos...

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Detalhes bibliográficos
Main Authors: Yue-Yue Zhou, Xiong-Fei Ji, Jian-Ping Fu, Xiao-Juan Zhu, Rong-Hua Li, Chang-Kao Mu, Chun-Lin Wang, Wei-Wei Song
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4503422?pdf=render
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