Mitoxantrone modulates a heparan sulfate-spike complex to inhibit SARS-CoV-2 infection

Abstract Spike-mediated entry of SARS-CoV-2 into human airway epithelial cells is an attractive therapeutic target for COVID-19. In addition to protein receptors, the SARS-CoV-2 spike (S) protein also interacts with heparan sulfate, a negatively charged glycosaminoglycan (GAG) attached to certain me...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Qi Zhang, Peter Radvak, Juhyung Lee, Yue Xu, Vivian Cao-Dao, Miao Xu, Wei Zheng, Catherine Z. Chen, Hang Xie, Yihong Ye
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2022-04-01
Serija:Scientific Reports
Online pristup:https://doi.org/10.1038/s41598-022-10293-x
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items