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Loss of receptor tyrosine kinase-like orphan receptor 2 impairs the osteogenesis of mBMSCs by inhibiting signal transducer and activator of transcription 3

Abstract Background Receptor tyrosine kinase-like orphan receptor 2 (Ror2) plays a key role in bone formation, but its signaling pathway is not completely understood. Signal transducer and activator of transcription 3 (Stat3) takes part in maintaining bone homeostasis. The aim of this study is to re...

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Auteurs principaux: Lizhen Lei, Zhuwei Huang, Jingyi Feng, Zijing Huang, Yiwei Tao, Xiaoli Hu, Xiaolei Zhang
Format: Artigo
Langue:Inglês
Publié: BMC 2020-03-01
Collection:Stem Cell Research & Therapy
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Accès en ligne:http://link.springer.com/article/10.1186/s13287-020-01646-2
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