Nanodrugs Detonate Lysosome Bombs

Cancer cell lysosomes contain various hydrolases and non-degraded substrates that are corrosive enough to destroy cancer cells. However, many traditional small molecule drugs targeting lysosomes have strong side effects because they cannot effectively differentiate between normal and cancer cells. M...

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Autors principals: Yuting Xiang, Niansheng Li, Min Liu, Qiaohui Chen, Xingyu Long, Yuqi Yang, Zuoxiu Xiao, Jia Huang, Xiaoyuan Wang, Yunrong Yang, Jinping Zhang, Chong Liu, Qiong Huang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2022-05-01
Col·lecció:Frontiers in Pharmacology
Matèries:
lysosomal membrane permeabilization
nanomaterials
nanodrugs
cancer treatment
chemodynamic therapy
magnetic nanoparticles
Accés en línia:https://www.frontiersin.org/articles/10.3389/fphar.2022.909504/full
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