MicroRNA-210-5p Contributes to Cognitive Impairment in Early Vascular Dementia Rat Model Through Targeting Snap25

Vascular dementia (VD) is the most common form of dementia in elderly people. However, little is understood about the role of microRNAs (miRNAs) involved in cognitive impairment in early VD. Here, a VD model induced by chronic cerebral ischemia and fetal bovine serum (FBS)-free cell model that detec...

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Autori principali: Zhenxing Ren, Junlong Yu, Zimei Wu, Wenwen Si, Xianqian Li, Yuqing Liu, Jianhong Zhou, Rudong Deng, Dongfeng Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018-11-01
Serie:Frontiers in Molecular Neuroscience
Soggetti:
vascular dementia
miR-210-5p
Snap25
cognitive impairment
synaptic loss
Accesso online:https://www.frontiersin.org/article/10.3389/fnmol.2018.00388/full
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