High GILT Expression Is Associated with Improved Survival in Metastatic Melanoma Patients Treated with Immune Checkpoint Inhibition

Gamma-interferon-inducible lysosomal thiol reductase (GILT) is critical for MHC class II restricted presentation of multiple melanoma antigens. There is variable GILT protein expression in malignant melanocytes in melanoma specimens. High GILT mRNA expression in melanoma specimens is associated with...

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Detalhes bibliográficos
Main Authors: Anngela C. Adams, Elizabeth S. Borden, Anne M. Macy, Nick Thomson, Haiyan Cui, Mark I. Gimbel, Melissa A. Wilson, Kenneth H. Buetow, Denise J. Roe, David J. DiCaudo, Jade Homsi, Karen Taraszka Hastings
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-04-01
Colecção:Cancers
Assuntos:
metastatic melanoma
GILT
immune checkpoint inhibitors
Acesso em linha:https://www.mdpi.com/2072-6694/14/9/2200
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