Hepatoprotective effects of vitamin C, DPPD, and L-cysteine against cisplatin-induced oxidative stress in male rats

Cisplatin (CP) is considered as a major antineoplastic drug against a broad spectrum of malignancies. CP acts on cancer cells by releasing free radicals which at the same time damage liver and kidney cells. The tissue specific toxicity of cisplatin to the kidneys is well documented. However, at hig...

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Main Authors: Hossam El-Din Mohamed Omar, Emad A. Ahmed, Sarry Abdel-Ghafar, Sohair Mohammed, Ahmed Y. Nasser
Formato: Artigo
Idioma:Inglês
Publicado em: TMKarpinski Publisher, Tomasz M. Karpiński 2012-01-01
Colecção:Journal of Biology and Earth Sciences
Assuntos:
Cisplatin
Hepatotoxicity
DPPD
Vitamin C
L-cysteine
Oxidative stress
Rats
Chemotherapy
Acesso em linha:http://www.journals.tmkarpinski.com/index.php/jbes/article/view/10/12
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