Clinical Relevance of Collagen Protein Degradation Markers C3M and C4M in the Serum of Breast Cancer Patients Treated with Neoadjuvant Therapy in the GeparQuinto Trial

<i>Background</i>: Remodeling of extracellular matrix through collagen degradation is a crucial step in the metastatic cascade. The aim of this study was to evaluate the potential clinical relevance of the serum collagen degradation markers (CDM) C3M and C4M during neoadjuvant chemothera...

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Main Authors: Malgorzata Banys-Paluchowski, Sibylle Loibl, Isabell Witzel, Christoph Mundhenke, Bianca Lederer, Christine Solbach, Thomas Karn, Frederik Marmé, Valentina Nekljudova, Christian Schem, Elmar Stickeler, Nicholas Willumsen, Morten A. Karsdal, Michael Untch, Volkmar Müller
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2019-08-01
Series:Cancers
Assuntos:
breast cancer
C3M
C4M
collagen degradation marker
neoadjuvant therapy
trastuzumab
lapatinib
Acceso en liña:https://www.mdpi.com/2072-6694/11/8/1186
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