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High MAF of EGFR mutations and high ratio of T790M sensitizing mutations in ctDNA predict better third‐generation TKI outcomes

Abstract Background Clinical detection of EGFR‐TKI resistance mechanism through tissue can be really challenging due to risks associated with the procedure. Thus, liquid biopsy, especially circulation tumor DNA (ctDNA) analysis, can be an adequate source for biomarker testing in targeted therapy. Ou...

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Detalhes bibliográficos
Main Authors: Yan Li, Fanshuang Zhang, Pei Yuan, Lei Guo, Ying Jianming, Jie He
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2020-06-01
Colecção:Thoracic Cancer
Assuntos:
MAF
Acesso em linha:https://doi.org/10.1111/1759-7714.13418
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