Integrated Glycome Strategy for Characterization of Aberrant LacNAc Contained N-Glycans Associated With Gastric Carcinoma

Aberrant glycosylation is not only a feature of malignant cell transformation, but also plays an important role in metastasis. In the present study, an integrated strategy combining the lectin microarrays and lectin cytochemistry was employed to investigate and verify the altered glycopatterns in ga...

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Hauptverfasser: Hanjie Yu, Xiaojie Li, Mengting Chen, Fan Zhang, Xiawei Liu, Jingmin Yu, Yaogang Zhong, Jian Shu, Wentian Chen, Haoqi Du, Kun Zhang, Chen Zhang, Jing Zhang, Hailong Xie, Zheng Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019-07-01
Schriftenreihe:Frontiers in Oncology
Schlagworte:
gastric carcinoma
glycosylation
lectin microarray
MALDI-TOF/TOF-MS
LacNAc
Online Zugang:https://www.frontiersin.org/article/10.3389/fonc.2019.00636/full
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