Animal-to-Human Translation Difficulties and Problems With Proposed Coding-in-Noise Deficits in Noise-Induced Synaptopathy and Hidden Hearing Loss

Noise induced synaptopathy (NIS) and hidden hearing loss (NIHHL) have been hot topic in hearing research since a massive synaptic loss was identified in CBA mice after a brief noise exposure that did not cause permanent threshold shift (PTS) in 2009. Based upon the amount of synaptic loss and the bi...

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Autori principali: Sara Ripley, Li Xia, Zhen Zhang, Steve J. Aiken, Jian Wang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-05-01
Serie:Frontiers in Neuroscience
Soggetti:
noise induced synaptopathy (NIS)
ribbon synapses
temporal processing
coding-in-noise deficit
cochlear efferent
fluctuation profile
Accesso online:https://www.frontiersin.org/articles/10.3389/fnins.2022.893542/full
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