X-Linked Lymphoproliferative Disease Type 1: A Clinical and Molecular Perspective

X-linked lymphoproliferative disease (XLP) was first described in the 1970s as a fatal lymphoproliferative syndrome associated with infection with Epstein–Barr virus (EBV). Features include hemophagocytic lymphohistiocytosis (HLH), lymphomas, and dysgammaglobulinemias. Molecular cloning of the causa...

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Detalhes bibliográficos
Main Authors: Neelam Panchal, Claire Booth, Jennifer L. Cannons, Pamela L. Schwartzberg
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-04-01
Colecção:Frontiers in Immunology
Assuntos:
X-linked lymphoproliferative disease 1
Epstein–Barr virus
SAP (signaling lymphocyte activation molecule-associated protein)
signaling lymphocytic activation molecule
primary immunodeficiency disease
hemophagocytic lymphohistiocytosis
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00666/full
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