TRIMming down to TRIM37: Relevance to Inflammation, Cardiovascular Disorders, and Cancer in MULIBREY Nanism

TRIpartite motif (TRIM) proteins are part of the largest subfamilies of E3 ligases that mediate the transfer of ubiquitin to substrate target proteins. In this review, we focus on TRIM37 in the normal cell and in pathological conditions, with an emphasis on the MULIBREY (MUscle-LIver-BRain-EYe) gene...

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Bibliographic Details
Main Authors: Benjamin Brigant, Valérie Metzinger-Le Meuth, Jacques Rochette, Laurent Metzinger
Format: Artigo
Language:Inglês
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
mulibrey
TRIM37
pericarditis
NF-κB
ubiquitin
Online Access:http://www.mdpi.com/1422-0067/20/1/67
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