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TRIMming down to TRIM37: Relevance to Inflammation, Cardiovascular Disorders, and Cancer in MULIBREY Nanism

TRIpartite motif (TRIM) proteins are part of the largest subfamilies of E3 ligases that mediate the transfer of ubiquitin to substrate target proteins. In this review, we focus on TRIM37 in the normal cell and in pathological conditions, with an emphasis on the MULIBREY (MUscle-LIver-BRain-EYe) gene...

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Autors principals: Benjamin Brigant, Valérie Metzinger-Le Meuth, Jacques Rochette, Laurent Metzinger
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2018-12-01
Col·lecció:International Journal of Molecular Sciences
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Accés en línia:http://www.mdpi.com/1422-0067/20/1/67
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