TrkB is highly expressed in NSCLC and mediates BDNF-induced the activation of Pyk2 signaling and the invasion of A549 cells

<p>Abstract</p> <p>Background</p> <p>Aberrant regulation in the invasion of cancer cells is closely associated with their metastatic potentials. TrkB functions as a receptor tyrosine kinase and is considered to facilitate tumor metastasis. Pyk2 is a non-receptor tyrosin...

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Hauptverfasser: Lu Yao, Li Chunyan, Zhang Ying, Zhang Qingfu, Luo Wenting, Guo Dawei, Zhang Siyang, Cui Zeshi, Qiu Xueshan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2010-02-01
Schriftenreihe:BMC Cancer
Online Zugang:http://www.biomedcentral.com/1471-2407/10/43
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