Discovery and Application of Postnatal Nucleus Pulposus Progenitors Essential for Intervertebral Disc Homeostasis and Degeneration

Abstract Intervertebral disc degeneration (IDD) results from the dysfunction of nucleus pulposus (NP) cells and the exhaustion of NP progenitors (ProNPs). The cellular applications of NP cells during IDD are currently limited due to the lack of in vivo studies showing whether NP cells are heterogene...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bo Gao, Bo Jiang, Wenhui Xing, Zaiqi Xie, Zhuojing Luo, Weiguo Zou
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Wiley 2022-05-01
Cyfres:Advanced Science
Pynciau:
intervertebral disc
lineage tracing
nucleus pulposus cell atlas
Sc‐RNA seq
stem cell therapy
Mynediad Ar-lein:https://doi.org/10.1002/advs.202104888
Tagiau: Ychwanegu Tag
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