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Tricky Topology: Persistence of Folded Human Telomeric i-Motif DNA at Ambient Temperature and Neutral pH

i-Motifs are four-stranded DNA structures formed from sequences rich in cytosine, held together by hemi-protonated cytosine-cytosine base pairs. These structures have been utilized extensively as pH-switches in DNA-based nanotechnology. Recently there has been an increasing interest in i-motif struc...

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Main Authors: Mahmoud A. S. Abdelhamid, Zoë A. E. Waller
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-01-01
Colecção:Frontiers in Chemistry
Assuntos:
DNA
Acesso em linha:https://www.frontiersin.org/article/10.3389/fchem.2020.00040/full
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