Recombinant Interleukin-1 Receptor Antagonist Conjugated to Superparamagnetic Iron Oxide Nanoparticles for Theranostic Targeting of Experimental Glioblastoma

Cerebral edema commonly accompanies brain tumors and contributes to neurologic symptoms. The role of the interleukin-1 receptor antagonist conjugated to superparamagnetic iron oxide nanoparticles (SPION–IL-1Ra) was assessed to analyze its anti-edemal effect and its possible application as a negative...

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Hauptverfasser: Maxim A. Shevtsov, Boris P. Nikolaev, Ludmila Y. Yakovleva, Anatolii V. Dobrodumov, Alexander V. Zhakhov, Anastasiy L. Mikhrina, Emil Pitkin, Marina A. Parr, Valerii I. Rolich, Andrei S. Simbircev, Alexander M. Ischenko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2015-01-01
Schriftenreihe:Neoplasia: An International Journal for Oncology Research
Online Zugang:http://www.sciencedirect.com/science/article/pii/S1476558614001663
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