Hyperoside Protected Against Oxidative Stress-Induced Liver Injury via the PHLPP2-AKT-GSK-3β Signaling Pathway In Vivo and In Vitro

Hyperoside, isolated from Drosera rotundifolia L., seeds of Cuscuta chinensis Lam., or Hypericum perforatum L., originally showed to possess an antifungal and antibacterial activity, while recently showed the protective effects against oxidative stress-induced liver injury. This study investigated s...

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Auteurs principaux: Haiyan Xing, Ruoqiu Fu, Caiyi Cheng, Yongqing Cai, Xianfeng Wang, Dongmei Deng, Xiaoyuan Gong, Jianhong Chen
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020-07-01
Collection:Frontiers in Pharmacology
Sujets:
hyperoside
liver injury
oxidative stress
pleckstrin homology domain leucine-rich repeat protein phosphatase 2
nuclear factor erythroid-2-related factor 2
glycogen synthase kinase 3β
Accès en ligne:https://www.frontiersin.org/article/10.3389/fphar.2020.01065/full
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