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Cytosolic extract induces Tir translocation and pedestals in EPEC-infected red blood cells.

Enteropathogenic Escherichia coli (EPEC) are deadly contaminants in water and food, and induce protrusion of actin-filled membranous pedestals beneath themselves upon attachment to intestinal epithelia. Pedestal formation requires clustering of Tir and subsequent recruitment of cellular tyrosine kin...

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Bibliographic Details
Main Authors: Alyson I Swimm, Daniel Kalman
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2211550?pdf=render
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