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Dissecting the function and assembly of acentriolar microtubule organizing centers in Drosophila cells in vivo.

Acentriolar microtubule organizing centers (aMTOCs) are formed during meiosis and mitosis in several cell types, but their function and assembly mechanism is unclear. Importantly, aMTOCs can be overactive in cancer cells, enhancing multipolar spindle formation, merotelic kinetochore attachment and a...

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Библиографические подробности
Главные авторы: Janina Baumbach, Zsofia Anna Novak, Jordan W Raff, Alan Wainman
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2015-05-01
Серии:PLoS Genetics
Online-ссылка:http://europepmc.org/articles/PMC4447278?pdf=render
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