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Dissecting the function and assembly of acentriolar microtubule organizing centers in Drosophila cells in vivo.

Acentriolar microtubule organizing centers (aMTOCs) are formed during meiosis and mitosis in several cell types, but their function and assembly mechanism is unclear. Importantly, aMTOCs can be overactive in cancer cells, enhancing multipolar spindle formation, merotelic kinetochore attachment and a...

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Bibliographische Detailangaben
Hauptverfasser: Janina Baumbach, Zsofia Anna Novak, Jordan W Raff, Alan Wainman
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2015-05-01
Schriftenreihe:PLoS Genetics
Online Zugang:http://europepmc.org/articles/PMC4447278?pdf=render
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