Angiogenesis by BMP-2-PDLLA-Biohybrids in Co-Culture with Osteoblasts and Endothelia

Adsorbate biohybrids for BMP-2 delivery based on electrospun PDLLA-nanofiber fleeces loaded with 0.6 μg/cm2 rhBMP-2COL (E. coli) strongly induced microvessel- like structures when incubated for 14 days in cocultures of human outgrowth endothelial cells (OEC) together with human primary osteoblasts (...

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Main Authors: Dohle Eva, Sowislok Andrea, Ghanaati Shahram, Jennissen Herber P.
Format: Artigo
Sprog:Inglês
Udgivet: De Gruyter 2021-10-01
Serier:Current Directions in Biomedical Engineering
Fag:
bmp-2 (e.coli)
bmp-2 (cho-cells)
angiogenic sprouts
proangiogenic effects
osteogenesis
Online adgang:https://doi.org/10.1515/cdbme-2021-2213
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