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Differentiation-dependent interpentameric disulfide bond stabilizes native human papillomavirus type 16.

Genetic and biochemical analyses of human papillomavirus type 16 (HPV16) capsids have shown that certain conserved L1 cysteine residues are critical for capsid assembly, integrity, and maturation. Since previous studies utilized HPV capsids produced in monolayer culture-based protein expression syst...

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Detalhes bibliográficos
Main Authors: Michael J Conway, Linda Cruz, Samina Alam, Neil D Christensen, Craig Meyers
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3139651?pdf=render
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