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Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning

Drug development is a lengthy and costly process that proceeds through several stages from target identification to lead discovery and optimization, preclinical validation and clinical trials culminating in approval for clinical use. An important step in this process is high-throughput screening (HT...

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Главный автор: Sigrid A. Langhans
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018-01-01
Серии:Frontiers in Pharmacology
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Online-ссылка:http://journal.frontiersin.org/article/10.3389/fphar.2018.00006/full
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