Nuclease Tudor-SN Is Involved in Tick dsRNA-Mediated RNA Interference and Feeding but Not in Defense against Flaviviral or Anaplasma phagocytophilum Rickettsial Infection.

Tudor staphylococcal nuclease (Tudor-SN) and Argonaute (Ago) are conserved components of the basic RNA interference (RNAi) machinery with a variety of functions including immune response and gene regulation. The RNAi machinery has been characterized in tick vectors of human and animal diseases but i...

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Main Authors: Nieves Ayllón, Victoria Naranjo, Ondrej Hajdušek, Margarita Villar, Ruth C Galindo, Katherine M Kocan, Pilar Alberdi, Radek Šíma, Alejandro Cabezas-Cruz, Claudia Rückert, Lesley Bell-Sakyi, Mária Kazimírová, Sabína Havlíková, Boris Klempa, Petr Kopáček, José de la Fuente
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4506139?pdf=render
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