Revealing transcription factor and histone modification co-localization and dynamics across cell lines by integrating ChIP-seq and RNA-seq data

Abstract Background Interactions among transcription factors (TFs) and histone modifications (HMs) play an important role in the precise regulation of gene expression. The context specificity of those interactions and further its dynamics in normal and disease remains largely unknown. Recent develop...

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Main Authors: Lirong Zhang, Gaogao Xue, Junjie Liu, Qianzhong Li, Yong Wang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-12-01
Colecção:BMC Genomics
Assuntos:
Transcription factor
Histone modification
Co-localization
Dynamics
Acesso em linha:http://link.springer.com/article/10.1186/s12864-018-5278-5
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