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Post-Translational Modification of GPX4 is a Promising Target for Treating Ferroptosis-Related Diseases

Glutathione peroxidase 4 (GPX4) is one of the most important antioxidant enzymes. As the key regulator of ferroptosis, GPX4 has attracted considerable attention in the fields of cancer, cardiovascular, and neuroscience research in the past 10 years. How to regulate GPX4 activity has become a hot top...

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Detalhes bibliográficos
Main Authors: Can Cui, Fei Yang, Qian Li
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Molecular Biosciences
Assuntos:
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmolb.2022.901565/full
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