Astrocytic αVβ3 integrin inhibits neurite outgrowth and promotes retraction of neuronal processes by clustering Thy-1.

Thy-1 is a membrane glycoprotein suggested to stabilize or inhibit growth of neuronal processes. However, its precise function has remained obscure, because its endogenous ligand is unknown. We previously showed that Thy-1 binds directly to α(V)β(3) integrin in trans eliciting responses in astrocyte...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Rodrigo Herrera-Molina, Renato Frischknecht, Horacio Maldonado, Constanze I Seidenbecher, Eckart D Gundelfinger, Claudio Hetz, María de la Luz Aylwin, Pascal Schneider, Andrew F G Quest, Lisette Leyton
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2012-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC3316703?pdf=render
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky