Effects of Host, Sample, and in vitro Culture on Genomic Diversity of Pathogenic Mycobacteria

Mycobacterium tuberculosis (M. tb), an obligate human pathogen and the etiological agent of tuberculosis (TB), remains a major threat to global public health. Comparative genomics has been invaluable for monitoring the emergence and spread of TB and for gaining insight into adaptation of M. tb. Most...

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Bibliografiset tiedot
Päätekijät: Abigail C. Shockey, Jesse Dabney, Caitlin S. Pepperell
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2019-06-01
Sarja:Frontiers in Genetics
Aiheet:
Mycobacterium tuberculosis
Mycobacterium bovis
genome evolution
within-host adaptation
bacterial genomics
hybridization capture
Linkit:https://www.frontiersin.org/article/10.3389/fgene.2019.00477/full
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