Quantitative Characterization of CD8+ T Cell Clustering and Spatial Heterogeneity in Solid Tumors

Quantitative characterization of the tumor microenvironment, including its immuno-architecture, is important for developing quantitative diagnostic and predictive biomarkers, matching patients to the most appropriate treatments for precision medicine, and for providing quantitative data for building...

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Main Authors: Chang Gong, Robert A. Anders, Qingfeng Zhu, Janis M. Taube, Benjamin Green, Wenting Cheng, Imke H. Bartelink, Paolo Vicini, Bing Wang, Aleksander S. Popel
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Oncology
Assuntos:
digital pathology
spatial patterns
spatial statistics
immuno-architecture
systems biology
Acceso en liña:https://www.frontiersin.org/article/10.3389/fonc.2018.00649/full
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