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Internal ribosomal entry site-mediated translation is important for rhythmic PERIOD1 expression.

The mouse PERIOD1 (mPER1) plays an important role in the maintenance of circadian rhythm. Translation of mPer1 is directed by both a cap-dependent process and cap-independent translation mediated by an internal ribosomal entry site (IRES) in the 5' untranslated region (UTR). Here, we compared m...

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Autores principales: Kyung-Ha Lee, Sung-Hoon Kim, Do-Yeon Kim, Seunghwan Kim, Kyong-Tai Kim
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2012-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC3360671?pdf=render
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