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Addressing bias in small RNA library preparation for sequencing: a new protocol recovers microRNAs that evade capture by current methods

Recent advances in sequencing technology have helped unveil the unexpected complexity and diversity of small RNAs. A critical step in small RNA library preparation for sequencing is the ligation of adapter sequences to both the 5’ and 3’ ends of small RNAs. Studies have shown that adapter ligation i...

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主要な著者: Jeanette eBaran-Gale, C. Lisa eKurtz, Michael eErdos, Christina eSison, Alice eYoung, Emily E Fannin, Peter S Chines, Praveen eSethupathy
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2015-12-01
シリーズ:Frontiers in Genetics
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オンライン・アクセス:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00352/full
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