Identification and Characterization of a Novel Long Noncoding RNA that Regulates Osteogenesis in Diet-Induced Obesity Mice

As a precursor to type 2 diabetes mellitus (T2D), obesity adversely alters bone cell functions, causing decreased bone quality. Currently, the mechanisms leading to alterations in bone quality in obesity and subsequently T2D are largely unclear. Emerging evidence suggests that long noncoding RNAs (l...

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Main Authors: Zhekai Hu, Wei Qiu, Yuedi Yu, Xingwen Wu, Fuchun Fang, Xiaofang Zhu, Xiaoyang Xu, Qisheng Tu, Thomas E. Van Dyke, Elise F. Morgan, Jake Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-04-01
Colecção:Frontiers in Cell and Developmental Biology
Assuntos:
long noncoding RNAs
diabetic bone diseases
diet-induced obese
epigenetics
LncR-DBD
BMP4
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcell.2022.832460/full
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