Copy Number Analyses Identified a Novel Gene: APOBEC3A Related to Lipid Metabolism in the Pathogenesis of Preeclampsia

BackgroundPreeclampsia is a heterogeneous and complex disease with its pathogenesis mechanism not fully elucidated. A certain subset of patients with preeclampsia exhibit disturbances in lipid metabolism before clinical symptoms. Moreover, there is a tendency for preeclampsia to run in families. Whe...

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Autori principali: Nan Liu, Yu-Na Guo, Xiao-Jin Wang, Jue Ma, Yun-Ting He, Fang Zhang, Hao He, Jin-Liang Xie, Xu Zhuang, Meng Liu, Jian-Hua Sun, Yan Chen, Jian-Hua Lin, Li-Kun Gong, Bing-Shun Wang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-05-01
Serie:Frontiers in Cardiovascular Medicine
Soggetti:
preeclampsia
APOBEC3A
lipid metabolism
copy number variation
genetics
Accesso online:https://www.frontiersin.org/articles/10.3389/fcvm.2022.841249/full
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