Cannabidiol Administration Prevents Hypoxia-Ischemia-Induced Hypomyelination in Newborn Rats

Neonatal hypoxia-ischemia (HI) is a risk factor for myelination disturbances, a key factor for cerebral palsy. Cannabidiol (CBD) protects neurons and glial cells after HI insult in newborn animals. We hereby aimed to study CBD’s effects on long-lasting HI-induced myelination deficits in newborn rats...

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Bibliografische gegevens
Hoofdauteurs: María Ceprián, Carlos Vargas, Laura García-Toscano, Federica Penna, Laura Jiménez-Sánchez, Svein Achicallende, Izaskun Elezgarai, Pedro Grandes, William Hind, M. Ruth Pazos, José Martínez-Orgado
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019-09-01
Reeks:Frontiers in Pharmacology
Onderwerpen:
hypoxia-ischemia
myelin
cannabidiol
newborn
rat
Online toegang:https://www.frontiersin.org/article/10.3389/fphar.2019.01131/full
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