Unraveling Hepcidin Plasma Protein Binding: Evidence from Peritoneal Equilibration Testing

Peptide hormone hepcidin regulates systemic iron metabolism and has been described to be partially bound to α2-macroglobulin and albumin in blood. However, the reported degree of hepcidin protein binding varies between <3% and ≈89%. Since protein-binding may influence hormo...

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Autori principali: Laura E. Diepeveen, Coby M. Laarakkers, Hilde P.E. Peters, Antonius E. van Herwaarden, Hans Groenewoud, Joanna IntHout, Jack F. Wetzels, Rachel P.L. van Swelm, Dorine W. Swinkels
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2019-08-01
Serie:Pharmaceuticals
Soggetti:
iron homeostasis
hepcidin
protein binding
peritoneal dialysis
Accesso online:https://www.mdpi.com/1424-8247/12/3/123
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