Modulation of Mismatch Repair and the SOCS1/p53 Axis by microRNA-155 in the Colon of Patients with Primary Sclerosing Cholangitis

Deficient mismatch repair (MMR) proteins may lead to DNA damage and microsatellite instability. Primary sclerosing cholangitis (PSC) is a risk factor for colitis-associated colon cancer. MiR-155 is suggested to act as a key regulating node, linking inflammation and tumorigenesis. However, its involv...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Monika Adamowicz, Iga Stukan, Piotr Milkiewicz, Andrzej Bialek, Malgorzata Milkiewicz, Agnieszka Kempinska-Podhorodecka
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2022-04-01
Serija:International Journal of Molecular Sciences
Teme:
miR-155
biomarker
microsatellite instability
inflammation
primary sclerosing cholangitis
colorectal cancer
Online pristup:https://www.mdpi.com/1422-0067/23/9/4905
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items