Epigenetic modulation of AREL1 and increased HLA expression in brains of multiple system atrophy patients

Abstract Multiple system atrophy (MSA) is a rare disease with a fatal outcome. To date, little is known about the molecular processes underlying disease development. Its clinical overlap with related neurodegenerative movement disorders underlines the importance for expanding the knowledge of pathol...

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Autori principali: Rasmus Rydbirk, Jonas Folke, Florence Busato, Elodie Roché, Alisha Shahzad Chauhan, Annemette Løkkegaard, Anne-Mette Hejl, Matthias Bode, Morten Blaabjerg, Mette Møller, Erik Hvid Danielsen, Tomasz Brudek, Bente Pakkenberg, Jorg Tost, Susana Aznar
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2020-03-01
Serie:Acta Neuropathologica Communications
Soggetti:
Multiple system atrophy
EWAS
Brain
Immune system
Hydroxymethylation
Neuroinflammation
Accesso online:http://link.springer.com/article/10.1186/s40478-020-00908-7
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